NTRK1 and glioblastoma: Current approaches for the treatment of recurrent glioblastoma involve non-targeted approaches (for details, refer to the excellent review articles [16,17]) such as surgery, radiotherapy or systemic cytotoxic chemotherapy, while targeted approaches involve the same general tactics (Receptor tyrosine kinases (RTK) inhibition and immune checkpoint inhibition) of treatment that will be discussed further in the review.