ACHE and Alzheimer disease: The current available treatments for AD can be categorized into pharmacological interventions targeting altered disease-related neurotransmitters (e.g., acetylcholinesterase inhibitors (AChEIs)such as galantamine and N-Methyl-D-aspartate receptor (NMDA) antagonists such as memantine) and non-pharmacological strategies primarily focusing on behavioural aspects [28].