Furthermore, a monoclonal antibody against the CMV UL44 immunoprecipitated both viral UL44 and some SLE antigens such as nucleoli, dsDNA, and ku70 [223]; and, SLE patients have displayed an increased level of CMV US31 leading to macrophage differentiation and inflammation activation [224]. The gene discussed is XRCC6; the disease is systemic lupus erythematosus.