In KEGG analysis, the top 10 enriched functional signaling pathways included glycine, serine, and threonine metabolism; acute myeloid leukemia; biosynthesis of amino acids; EGFR tyrosine kinase inhibitor resistance; ErbB signaling pathway; longevity regulating pathway, choline metabolism in cancer; HIF-1 signaling pathway; cholinergic synapse; and glutamatergic synapses. The gene discussed is EGFR; the disease is cancer.