GCG and Hyperglycemia: In addition to their anti-inflammatory effects and improvement of hyperglycemia, SCFAs also exert antidiabetic effects through insulin secretion in a glucose-dependent manner by stimulating the secretion of glucagon-like peptide 1 (GLP-1) via the free fatty acid receptors, FFAR2 and FFAR3, located on enteroendocrine cells [53].