Combining the results of this article with liver imagining and gut microbiota analysis, as in previous publications [14,27,28,85], could help understand the effects of dietary fat modification and carriage of CC or GG genotype of PNPLA3 gene on SCFAs and BCAAs and their possible effect on NAFLD. The gene discussed is PNPLA3; the disease is metabolic dysfunction-associated steatotic liver disease.