Animal models suggest that ozone significantly interferes with neural physiology by increasing lipid peroxidation, reducing dopaminergic neurons, increasing interleukin-6 (IL-6) and tumor necrosis factor α (TNF-α), and accumulating amyloid-b and a-synuclein, which are pathologic proteins in Alzheimer’s and Parkinson’s disease respectively [7,12,13,14,15]. The gene discussed is IL6; the disease is Parkinson disease.