In addition, the main compounds in Pule’an Tablets might exert the therapeutical effect through the signaling pathways of prostate cancer, endocrine resistance, fluid shear stress and atherosclerosis, lipids and atherosclerosis, proteoglycans in cancer, bladder cancer, the IL-17 signaling pathway, the pathways in cancer, and relaxin signaling. This evidence concerns the gene IL17A and prostate cancer.