PTGS2 and benign prostatic hyperplasia: The results showing an inhibitory effect of the EH treatment on COX2 levels were in accordance with another in vivo study involving testosterone propionate-induced benign prostatic hyperplasia in castrated Sprague Dawley rats, in which decreased COX2 expression and NFκB pathway down-regulation were noted after treatment with n-butanolic Epilobium angustifolium L. extracts compared to a positive control of finasteride [79].