The anti-Alzheimer’s actions of lignans, including protecting nerve cells and reducing dementia, are linked with their antioxidant capacity, lowering acetylcholinesterase (AChE) activity and vascular disease management in addition to manipulating many inflammatory cytokine pathways, such as NF-kB, NO, TNF-α, and IL-1β pathways [8,9,10,11]. This evidence concerns the gene ACHE and dementia.