However, to date, there has been a lack of experimental evidence supporting this diagnostic and personalized approach in arterial hypertension, and we hope that current large RCTs, such as the coArtHA trial, aiming to identify the most effective treatment strategies to control arterial hypertension in sub-Saharan Africa and including focused echocardiography and BNP testing in untreated and clinically uncomplicated arterial hypertension, will allow us to obtain a database that can help us to implement BNP testing in clinical practice [133]. The gene discussed is NPPB; the disease is Hypertension.