Antiphospholipid syndrome (APS) is an acquired thrombophilia characterized by the presence of antiphospholipid antibodies, including lupus anticoagulant (LAC), beta-2 glycoprotein 1 antibodies (B2GPI), and anticardiolipin antibodies, which are directed against plasma proteins bound to anionic phospholipids [110]. This evidence concerns the gene APOH and autoimmune polyendocrinopathy.