The NHANES analyses also showed very little change in the prevalence of CKD in patients with diabetes as defined by a persistent urine albumin-to-creatinine ratio of ≥30 mg/g or a persistent eGFR of <60 mL/min per 1.73 m2, from 28.4% (1988 to 1994) to 26.2% (2009 to 2014) [11]. This evidence concerns the gene ALB and chronic kidney disease.