In particular, the observed AUC values were equal to 0.87 for NFPAs, 0.89 for GH-secreting adenomas, 0.95 for prolactinomas, 0.94 for ACTH-secreting adenomas, 0.96 for FSH/LH-secreting adenomas, 0.95 for TSH-secreting adenomas, and 0.74 pluri-hormonal secreting adenomas. Here, POMC is linked to adenoma.