The autoimmune response in the pemphigoid group is focused on specific antigens of the dermal-epidermal/stromal-epithelial junction: Bullous pemphigoid is associated with antibodies against antigen 180 bullous pemphigoid (BP180), 230 bullous pemphigoid (BP230), and mucous membrane pemphigoid (MMP), which involves several autoantigens such as BP180, laminin-332, α6β4 integrin and type VII collagen. The gene discussed is DST; the disease is bullous pemphigoid.