MBI existed in 32.4% of PD patients atthe time of diagnosisAffective dysregulation, decreased motivation and impulse dyscontrolwere the most frequently affected MBI domainsMBI was associated with higher scores in UPDRS part IIIMBI was associated with lower scores in memory and Stroop color reading tests that assess frontal dysfunctionMBI was associated with reduced DAT availability in the anterior caudate and anterior putamen. The gene discussed is SLC6A3; the disease is Parkinson disease.