FGFR fusions were reported for the first time in 2012, in a glioblastoma tumor; they were rarely observed (0.2%) in non-small cell lung cancer, and predominantly (but not exclusively) in squamous cell carcinomas (3% of them harboring FGFR3-TACC3 rearrangement). The gene discussed is FGFR3; the disease is squamous cell carcinoma.