In the AP group, hyperemia was positively correlated with MPO (rho = 0.697, p < 0.001), CD45 (rho = 0.644, p < 0.001), HMGB1 (rho = 0.518, p < 0.001), and TNFα intestinal expression (rho = 0.722, p < 0.001), as well as IL-6 (rho = 0.585, p < 0.001) and TNFα pancreatic expression (rho = 0.789, p < 0.001). The gene discussed is HMGB1; the disease is alkaline phosphatase measurement.