TRPV4 and hypertensive disorder: In the last decade, research on TRPV4 has mainly focused on its mechanosensory function, which is involved in various physiological and pathological processes, such as vasoconstriction [20], gastrointestinal motility [21], hair growth cycle [22,23], fibrosis [24,25,26], scleroderma [27], hypertension [28,29], gastric cancer [30,31], rosacea [32,33], brain injury [34], and pancreatitis [35,36].