There was a difference when stratifying according to hyperandrogenemia, with APCS, ApoE and ApoA1 higher in hyperandrogenemia (p < 0.01, p < 0.04 and p < 0.01, respectively), while PAPPA was decreased in hyperandrogenemia (p < 0.01). The gene discussed is PAPPA; the disease is polycystic ovary syndrome.