The pathophysiology of AD is not fully understood but includes inflammation [14] and protein misfolding [15]; β-amyloid is formed from native amyloid precursor protein (APP), and misassembly of amyloid precursor protein (APP) fragments results in toxic oligopeptide formation [14]; and β-amyloid fragments, mainly the amyloid beta 42 (Aβ-42) isoform, exhibit cytotoxic properties. Here, APP is linked to Alzheimer disease.