NFE2L2 and diabetes mellitus: Recently, several preclinical studies have been focusing on searching for substances that inhibit the impairment in the Nrf2 pathway induced by diabetes in neural and vascular retinal cells: acteoside [428], maslinic acid [4], astragaloside IV [393], urolithin A [422], hydroxysafflor yellow A [392], carnosol [395], astaxanthin [398], and amygdalin [429], among others.