SREBF1 and metabolic syndrome: Capparis spinosa represents a traditional plant previously used to treat dyslipidemia, reduce SREBP1c expression, and induce carnitine palmitoyltransferase 1 (CPT1) expression in MASH rat models, providing evidence for the favorable therapeutic effects of Capparis spinosa for ameliorating steatosis via modification of de novo lipogenesis and the β-oxidation pathway genes [77].