In the LNM-positive group compared to the control adenoma, there were significant increases in gene expression for CCL15, SSX1, and KRT5 genes (Figure 2A), alongside significant decreases in HLA-E, ITPK1, ANXA1, and TXNIP genes (Figure 2B) across the head, proximal stalk, and distal stalk regions. The gene discussed is ITPK1; the disease is adenoma.