The LINC00645 is induced by TGF-β and plays a key role in TGF-β-induced mesenchymal differentiation by sponging miR-205-3p, which in turn targets ZEB1, thus promoting ZEB1 expression as well as TGF-β-induced glioma cell invasion and migration [77]. The gene discussed is TGFB1; the disease is central nervous system cancer.