While the variant rs11096957 (p.Asn241His) in the TLR10 gene identified in our study is common, with an allele frequency of 0.3691 in the European, non-Finnish population, it was absent in all controls while present in all MEN1 patients with adrenocortical tumor in either a heterozygous or homozygous state. The gene discussed is TLR10; the disease is adrenal cortex neoplasm.