Regarding the prevalence of MMRd ECs across the different histotypes of EC, undifferentiated/dedifferentiated carcinoma (UEC/DEC) is the most common MMR deficient subtype (44%) followed by neuroendocrine carcinoma (42.9%), high-grade endometrioid carcinoma (39.7%), mixed forms (33.3%), low-grade endometrioid carcinoma (24.7%), clear cell carcinoma [40] (9.8%) and carcinosarcoma [41] (7.3%). The gene discussed is MRC1; the disease is carcinoma.