Additionally, Ionescu et al. [42] found a strong statistically significant correlation between IL-6 concentration in tears and the degree of KC advancement (r = 0.56, p < 0.01), keratometry (r = 0.55, p < 0.02), pachymetry (r = −0.64, p < 0.048), and corneal hysteresis (r = −0.53, p < 0.02). The gene discussed is IL6; the disease is keratoconus.