Finally, a positive correlation between lipid oxidation and the Th22/Th17 pathway at a single-cell level has been demonstrated: Fer-1 (a specific inhibitor of ferroptosis) decreases inflammation in mice with imiquimod-induced psoriasis, with significantly decreased expression of TNF, IL-6, IL-1α, IL-1β, IL-17, IL-22, and IL-23 [139]. The gene discussed is TNF; the disease is psoriasis.