S1PR3 and systemic lupus erythematosus: Another group reported differentially methylated genes, including sphingosine-1-phosphate receptor 3 (S1PR3), CD300 molecule-like family member B (CD300LB), and NACHT, LRR, and PYD domains-containing protein 2 (NLRP2) in SLE CD4+ T cells using a genome-wide DNA methylation experiment [84].