They found that key genes involved in tumor cell proliferation and metastasis formation (e.g., IL6, CXCL8, IL15, OPN, VEGFA, VEGFD, FGF17, MMP2, MMP3, TIMP1, PRKAA, and PRKACA) in the Shenzhou 8 space mission responded similarly to μg in subsequent ten-d RPM experiments in an antiproliferative manner with often opposite effects in PF. The gene discussed is MMP3; the disease is neoplasm.