MAPK3 and breast cancer: In addition, MDA-MB-231 BC cells exposed to PF maneuvers revealed an early upregulation of ICAM1, CD44, and ERK1 mRNAs after the first parabola (P1) and a delayed upregulation of NFKB1, NFKBIA, NFKBIB, and FAK1 after the last parabola (P31).