C2, with the most favorable prognosis, exhibited similarity to the active Hippo (AH) pathway subgroup [18], CCL’s HCC subclass [19], CTNNB1 activating mutations subclass (Boyault’s G5/G6) [20], and the well-differentiated subclass (Hoshida’s S3) [21]. Here, CTNNB1 is linked to hepatocellular carcinoma.