In PCOS, lncRNA NEAT1 has elevated levels in serum and granulosa cells; however, lncRNA MALAT1 is repressed. Their involvement in PCOS development relies on adjusting miR-30d-5p and miR-30a-5p, which affects IRS-2, AR, and FST expression. Here, MALAT1 is linked to polycystic ovary syndrome.