Hsp27-overexpressing KT breast cancer cells showed increased resistance to ultraviolet ray C (UVC) and interferon lethality [28], and our recent study also found that phosphorylated Hsp27 promoted ADR resistance in MCF-7 and MDA-MB-231 breast cancer cells by regulating DNA damage repair protein c-Myc dual phosphorylation [29]. Here, HSPB1 is linked to breast cancer.