As for the diagnostic values of serum H19 between non-hypertensive CIS cases and healthy control subjects, the AUC was 0.95 (95% CI = 0.88–1.01) at p < 0.0001 and the optimal sensitivity and specificity were 95 and 100%, respectively, with a cutoff value of 1.249 (Figure 3B). This evidence concerns the gene H19 and in situ carcinoma.