RSD and RGD motifs not only play an important role in other pathogens’ infection, such as group A Streptococcus, which can promote binds to human integrins alphavbeta3 and alphaIIbbeta3 (Equine herpesvirus 1 entry via endocytosis is facilitated by alphaV integrins and an RSD motif in glycoprotein D [43,44]); however, they are also involved in cell adhesion and viability [45,46]. Here, ACKR1 is linked to infection.