Existing studies have investigated the use of specific CAMs, including the activated leukocyte cell adhesion molecule (ALCAM), intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1), neural cell adhesion molecule 1 (NCAM-1), and L-selectin, as biomarkers in LN [51,72,73,75,80,94,95,96,97,98,99]. The gene discussed is ALCAM; the disease is lobular neoplasia.