For instance, the signature of type I interferon (IFN) is predominantly observed in the kidneys and skin of individuals diagnosed with proliferative LN [3,24], whereas patients with membranous LN exhibit different transcriptomic patterns [24], and transcriptome-based investigations using animal models have provided insights into the progression and phases of LN development [25]. The gene discussed is IFNA1; the disease is lobular neoplasia.