Bioinformatic analysis in the Cancer Cell Line Encyclopedia (https://sites.broadinstitute.org/ccle, accessed on 1 March 2019) allowed us to select lung cancer cell lines with low (A549, NCI-H1299, Calu-6, NCI-H1975, NCI-H2228, NCI-H441, LX-1, SKMES and SK LU-1) or relatively high (HCC827 and its derivative HCC827-GR5, NCI-H1437, NCI-H727 and NCI-H2342) endogenous expression of PRODH. The gene discussed is PRODH; the disease is cancer.