Li et al. found that miR-331-3p, which is downregulated in NSCLC tumors, is able to control EMT, migration and metastasis dissemination of NSCLC cells through the Rac1/PAK1/β-catenin pathway by directly targeting VAV2 and HER2 expression [63]. This evidence concerns the gene PAK1 and non-small cell lung carcinoma.