The profile of the TGFB ligands differed markedly in the pbDMG brain stem/pons and normal pons tissues, whereby in the pbDMG samples, the TGFB2 mRNA expression was significantly higher than those of the TGFB1 (1.54-fold increase; p = 4.1 × 10−4) and TGFB3 (2.25-fold increase; p < 0.0001), suggesting the specific upregulation of the TGFB2 isoform in the pbDMG tumor tissue. Here, TGFB1 is linked to neoplasm.