INS and preeclampsia: Although most studies investigating miR-200b-3p are related to its regulation and mechanism on malignant phenotype tumors [46], miR-200b-3p also exhibits modulatory roles in many physiological and pathological processes, including the formation of insulin-producing cells [47], fetal cartilage differentiation [48], preeclampsia [49], wound healing [50], and neuropathological disorders [51].