BCL3 and breast cancer: To determine the effects of Bcl3 inhibition on breast cancer cell survival, a pool of Bcl3-specific siRNAs were transfected into four breast cancer cell lines (p53wt = MCF-7 and ZR751; p53mut = T47D and BT474), before cell viability was analysed using cell titre blue in comparison to that of cells transfected with non-targeting control siRNA (scRNA).