Several subtypes of AML, like fms-related receptor tyrosine kinase 3 (FLT3)-mutated AML, AML harboring the translocation AML-ETO, acute promyelocytic leukemia, and trisomy 21-acute megakaryocytic leukemia, are associated with high levels of miR-125b [69]. The gene discussed is RUNX1T1; the disease is acute myeloid leukemia.