Semaglutide exhibited pro-autophagy via the increased expression of LC3II, Atg7, Beclin-1, and P62, as well as an anti-apoptotic effect via the inhibition of the Bax system that was induced by Aβ25-35 in an AD model (SH-SY5Y cells with Aβ25-35) [105]. This evidence concerns the gene BECN1 and Alzheimer disease.