Proteomic analysis of ischemia-associated ncAA-containing proteins also revealed that bladder ischemia elicits differential (post-translational) modifications of the proteins involved in cellular stress response, including heat shock 70 kDa protein 1A (Hspa1a, P0DMW0), heat shock protein beta-6 (Hspb6, P97541), serpin H1 (Serpinh1, P29457), and elongation factor 1-delta (Eef1d, Q68FR9). This evidence concerns the gene HSPB6 and ischemia.