We found two CFS-associated genes Myo3b (aphidicolin-induced CFS) and Kcnq5 (BrdU-induced CFS) in Pla-WT and another two, Tnni3k (aphidicolin-induced CFS) and Cfap61 (folic acid-induced CFS) in Pla-KO1, i.e., 15% and 29% of the up-DPpGCs, respectively. Here, KCNQ5 is linked to myalgic encephalomeyelitis/chronic fatigue syndrome.