We found that disabled-1, Dab1, the second ranked one, has been characterized as a large CFS gene that is mapped within the FRA1B CFS and inactivated in multiple cancers [10,21], while AUTS2 (rank 5) maps in FRA7J, NRXN1 (rank 16) in FRA2D, PRKG1 (127) in FRA10C [10], and SDK1 (14) in FRA7B [22]. This evidence concerns the gene NRXN1 and cancer.