The SCGB1A1+MUC5B+ club cells from IPF patients expressed mucin (SPDEF, MUC5B, TFF3, and AGR2) and chemoattractant cytokines for immune cells (CXCL1, CXCL6, CXCL8, and CX3CL1). Here, SCGB1A1 is linked to idiopathic pulmonary fibrosis.