In this study, we aim to assess cardiovascular risk using SCORE2 and SCORE2OP to evaluate the association between the endothelial biomarkers VCAM-1, ICAM-1, epicardial fat, and sleep study variables in order to improve the current clinical practice, and better understand the short- and long-term cardiovascular risks in patients with OSA. The gene discussed is ICAM1; the disease is obstructive sleep apnea syndrome.