Thus, STAT3 SNPs have been associated with autoimmune thyroid diseases (AITD) [83], STAT4 SNPs with early disease onset and severity of autoimmune diseases, including systemic lupus erythematosus [84] and rheumatoid arthritis [85], STAT5A SNPs with atopic dermatitis [86] and STAT6 SNPs with asthma [87]. The gene discussed is STAT3; the disease is autoimmune disease.