NQO2 and ovarian neoplasm: Two other promoter polymorphisms, C3395G (rs2070998) and I/D-29, and one exon 1 SNP A3968C (rs2071002), were analyzed for a functional role, but no differences in NQO2 activity or expression were identified in bladder and ovarian tumors [19], in contrast to later studies discussed above, suggesting that the genetic variant effect on the NQO2 expression might be tissue-dependent [17,18].