The significance of the search for rare variants is further underscored by the identification of disease genes closely related to ASD, with more than 100 such genes, including SHANK3, CNTNAP2, and NLGN4X, implicated in both ASD and epilepsy [20]; see also https://gene.sfari.org/ (accessed on 30 November 2023). This evidence concerns the gene SHANK3 and epilepsy.